ISSN 1662-4009 (online)

ey0015.11-13 | Adipose tissue – a main source of miRNAs | ESPEYB15

11.13 Adipose-derived circulating miRNAs regulate gene expression in other tissues

T Thomou , M Mori , J Dreyfuss , M Konishi , M Sakaguchi , C Wolfrum , T Nageswara Raa , J Winnay , R Garcia-Martin , S Grinspoon , P Gorden , R Kahn

To read the full abstract: Nature 2017, 542, 450–455Adipose tissue is no longer considered a passive energy store. Instead, it is well established as an important endocrine contributor. Here, the authors comprehensively show that the function of the adipose tissue as an endocrine organ is not limited to classical adipokines, but also includes miRNAs and maybe other non-coding RNAs. This study...